| Date | Location | Result | |
| Nov 10, 2012 | Jacksonville, Fla. | North Florida 3, USC Upstate 0 (25-21,25-23,25-13) | Box score |
| Nov 09, 2012 | Jacksonville, Fla. | Jacksonville 3, USC Upstate 2 (18-25,26-24,19-25,25-21,15-10) | Box score |
| Nov 08, 2012 | Savannah, Ga. | USC Upstate 3, Savannah State 1 (25-15,25-13,24-26,25-11) | Box score |
| Nov 06, 2012 | Spartanburg, S.C. | Mercer 3, USC Upstate 0 (25-17,25-16,25-17) | Box score |
| Nov 03, 2012 | Spartanburg, S.C. | Florida Gulf Coast 3, USC Upstate 0 (25-22,25-19,25-21) | Box score |
| Nov 02, 2012 | Spartanburg, S.C. | USC Upstate 3, Stetson 0 (25-11,25-11,25-20) | Box score |
| Oct 27, 2012 | Nashville, TN | Lipscomb 3, USC Upstate 0 (25-20,25-18,25-14) | Box score |
| Oct 26, 2012 | Highland Heights, Ky | Northern Kentucky 3, USC Upstate 0 (25-20,25-22,25-15) | Box score |
| Oct 19, 2012 | Spartanburg, S.C. | USC Upstate 3, ETSU 2 (16-25,25-17,26-24,25-27,15-10) | Box score |
| Oct 16, 2012 | Macon, Ga. | USC Upstate 3, Mercer 0 (25-19,25-19,25-14) | Box score |
| Oct 13, 2012 | Spartanburg, S.C. | USC Upstate 3, Jacksonville 0 (25-22,25-17,27-25) | Box score |
| Oct 12, 2012 | Spartanburg, S.C. | North Florida 3, USC Upstate 2 (25-23,23-25,24-26,25-21,16-14) | Box score |
| Oct 09, 2012 | Spartanburg, S.C. | USC Upstate 3, Kennesaw State 0 (25-18,25-15,25-23) | Box score |
| Oct 06, 2012 | Spartanburg, S.C. | Northern Kentucky 3, USC Upstate 1 (25-20,25-21,21-25,25-23) | Box score |
| Oct 05, 2012 | Spartanburg, S.C. | Lipscomb 3, USC Upstate 0 (25-21,25-21,25-20) | Box score |
| Oct 02, 2012 | Spartanburg, S.C. | USC Upstate 3, Savannah State 0 (25-5,25-15,25-17) | Box score |
| Sep 29, 2012 | Fort Myers, Fla. | Florida Gulf Coast 3, USC Upstate 0 (25-22,25-23,25-20) | Box score |
| Sep 28, 2012 | DeLand, Fla. | USC Upstate 3, Stetson 0 (25-19,25-23,25-14) | Box score |
| Sep 25, 2012 | Boiling Springs, NC | GWU 3, USC Upstate 1 (25-23,25-17,17-25,25-16) | Box score |
| Sep 21, 2012 | Johnson City, Tenn. | ETSU 3, USC Upstate 0 (25-20,25-23,25-15) | Box score |
| Sep 18, 2012 | Kennesaw, Ga. | Kennesaw State 3, USC Upstate 1 (29-27,25-17,23-25,29-27) | Box score |
| Sep 15, 2012 | Chicago, Ill. | USC Upstate 3, Chicago State 0 (25-14,25-15,25-18) | Box score |
| Sep 14, 2012 | Chicago, Ill. | Loyola Chicago 3, USC Upstate 1 (25-18,23-25,25-20,25-15) | Box score |
| Sep 14, 2012 | Chicago, Ill. | DePaul 3, USC Upstate 0 (25-15,25-16,25-13) | Box score |
| Sep 11, 2012 | Spartanburg, S.C. | USC Upstate 3, Asheville 1 (25-20,20-25,30-28,25-15) | Box score |
| Sep 01, 2012 | Charleston, S.C. | Canisius 3, USC Upstate 1 (27-25,25-21,21-25,25-18) | Box score |
| Sep 01, 2012 | Charleston, S.C. | Furman 3, USC Upstate 0 (25-17,25-20,25-18) | Box score |
| Aug 31, 2012 | Charleston, S.C. | Charleston Southern 3, USC Upstate 2 (25-23,12-25,25-17,25-27,15-4) | Box score |
| Aug 25, 2012 | Chattanooga, Tenn. | USC Upstate 3, Alcorn State 0 (25-6,25-5,25-11) | Box score |
| Aug 25, 2012 | Chattanooga, Tenn. | Chattanooga 3, USC Upstate 1 (25-21,25-21,19-25,32-30) | Box score |
| Aug 24, 2012 | Chattanooga, Tenn. | USC Upstate 3, Tennessee Tech 0 (26-24,25-17,25-13) | Box score |